Vaginal dryness is one of the most common and frustrating symptoms women face during and after menopause. Left untreated, it can impact intimacy, urinary health, and overall quality of life. But thanks to advances in medicine, there are more solutions than ever to help you reclaim your comfort and confidence.
Here are the top 5 treatments for vaginal dryness after menopause, updated with the latest research for 2025.
Let’s dive in!
1. Local Vaginal Estrogen Therapy
Vaginal estrogen remains one of the most effective treatments for restoring moisture and tissue health after menopause. Unlike systemic hormone therapy, vaginal estrogen works locally — delivering small amounts of estrogen directly where it’s needed without significantly affecting blood hormone levels.
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Common Forms:
- Vaginal creams (like Premarin® Vaginal Cream)
- Vaginal tablets (such as Vagifem®)
- Vaginal rings (e.g., Estring®)
- Thickens vaginal tissue
- Restores natural lubrication
- Reduces risk of urinary tract infections (UTIs)
- A painless laser gently treats the vaginal walls
- Stimulates natural moisture and elasticity
- Typically requires three sessions spaced six weeks apart, with annual maintenance
- HRT is no longer as controversial as it once was; major studies, like the Women’s Health Initiative follow-ups, have clarified its risks and benefits.
- Digestive health benefits: HRT can improve gut motility, helping with constipation associated with menopause.
- Urinary health: Systemic estrogen strengthens the urinary tract lining, reducing the risk of recurrent UTIs.
- Oral tablets
- Patches
- Gels
- Injections
- Blood is drawn, spun down to concentrate platelets, and injected into targeted vaginal areas.
- Encourages natural tissue healing and collagen growth.
Benefits: - Non-hormonal
- Improves moisture and intimacy
- May reduce mild urinary incontinence
- Replens Long-Lasting Vaginal Moisturizer
- AH! YES VM Vaginal Moisturizer
- Uberlube Luxury Lubricant
- Moisturizers are for ongoing moisture support (used several times per week)
- Lubricants are for use during intimacy
Benefits:
👉 Learn more about vaginal estrogen therapy here.
Source: Mayo Clinic
2. MonaLisa Touch® Laser Therapy
MonaLisa Touch® is a revolutionary non-hormonal treatment that uses fractional CO₂ laser technology to stimulate collagen production, improve blood flow, and restore vaginal health.
How it Works:
Perfect for women who can’t or prefer not to use hormone therapies (e.g., breast cancer survivors).
👉 Learn more about MonaLisa Touch®.
Source: MonaLisaTouch.com
3. Systemic Hormone Replacement Therapy (HRT)
Full-body HRT — using a combination of estrogen and sometimes progesterone — can also significantly improve vaginal dryness along with other menopause symptoms like hot flashes, night sweats, and mood swings.
Key Updates for 2025:
Forms Available:
👉 Consult your healthcare provider to see if HRT is right for you.
Source: American College of Obstetricians and Gynecologists (ACOG)
4. Platelet-Rich Plasma (PRP) Therapy – The O-Shot®
PRP therapy, often called the O-Shot®, uses your own blood-derived growth factors to rejuvenate vaginal tissue, improve sensitivity, and enhance natural lubrication.
How it Works:
👉 Learn more about The O-Shot® here.
Source: O-Shot® Official Site
5. Vaginal Moisturizers and Lubricants
For many women, regular use of over-the-counter vaginal moisturizers and lubricants can provide significant relief — especially when combined with other treatments.
Top Recommended Products:
Difference:
👉 Shop trusted vaginal moisturizers and lubricants.
Source: Mayo Clinic Vaginal Atrophy Treatment Guide
Final Thoughts: You Have Options
Vaginal dryness after menopause is extremely common — but you don’t have to just “live with it.”
Today’s treatments are safer, more effective, and more customizable than ever before.
✅ Whether you prefer hormone-free laser therapy, localized estrogen, full-body HRT, or a natural approach, there’s a solution that can help restore your comfort and confidence.